A Connection Between An Animal Cell Is Known As A Why Cruciferous And Red Grapes Can Prevent The Cancer?

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Why Cruciferous And Red Grapes Can Prevent The Cancer?

Cruciferous vegetables are widely used in the prevention of cancer diet. The important ingredient in cruciferous vegetables is called I3C. I3C is catalyzed by stomach acid to diindolylmethane (DIM). DIM is believed to be the beneficial active ingredient in cruciferous vegetable I3C. Both I3C and DIM stimulate biochemical pathways to metabolize potential carcinogens. I3C has been shown to reduce the spread of many forms of cancer including breast cancer, prostate cancer, endometrial cancer, colon cancer and leukemia.

Animal studies have shown that long-term administration of I3C reduced spontaneous breast tumor development by 50 percent and endometrial tumors by 24 percent. Additionally, animal models show that supplementation with I3C prior to exposure to a known carcinogen reduced the development of breast tumors by 70-90 percent. Studies on human breast cancer cell lines show that DIM inhibits the growth of estrogen-dependent and estrogen-independent cancer cells by approximately 60 percent. This study also showed that DIM binds to estrogen receptors in these cells, preventing estradiol, the bad estrogen, from binding to the estrogen receptor. Other evidence shows that I3C decreases the growth of the blood supply of cancer cells and the spread of cancer cells locally, and that it protects the liver from carcinogens.

Another interesting feature of DIM is that it exhibits anti-androgenic activity. Research shows that DIM inhibits dihydrotestosterone (DHT) from binding to androgen receptors in androgen-dependent human prostate cancer cells, decreasing the induction of DNA synthesis. DIM also reduced prostate-specific antigen (PSA) levels. This protein is often measured to assess the risk of prostate cancer. Additional research has shown that DIM induces cell cycle arrest and apoptosis in prostate cancer cells, as well as regulating several genes.

Resveratrol is a natural polyphenol found in high concentrations in the skins of red grapes, berries and peanuts. It is found in high concentration in red wine and red grape juice. Resveratrol has been widely studied for its antioxidant, anti-inflammatory, anti-cancer and anti-aging properties. Studies with resveratrol show that this polyphenol inhibits aromatase activity in breast cancer cells, a fact that is particularly important given that aromatase is expressed at a higher level in breast cancer tissue than in surrounding healthy tissue. In fact, resveratrol inhibits the conversion of estrogen from testosterone and decreases the synthesis of the aromatase enzyme, thus indicating that it may support the health of individuals concerned about breast cancer.

Research also shows that red wine extracts reverse aromatase-induced tissue enlargement and other neoplastic changes in breast tissue. In conclusion, resveratrol decreases tumor initiation, promotion and progression and induces apoptosis in many types of cancer cells. This doesn’t mean we should drink more wine, because alcohol can also enhance aromatase activity and damage liver and brain function. Eating red grapes is a much better choice than drinking wine.

Cruciferous vegetables have a lot of fiber. We need a good digestive system to absorb valuable nutrients. Acupuncture can help improve the function of the digestive system, so we can digest those vegetables more efficiently. We also need to see how much we can eat those vegetables, too much of a good thing may not be good for the body. Cooked cruciferous vegetables are much easier to digest than raw ones.

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